Peptipedia › Glossary › Microdosing
Dosing & use
Microdosing
Microdosing - Deliberately starting with a dose well below the usual standard or manufacturer recommendation, to first test your own reaction and tolerability and work up only in small steps ("start low, go slow").
Also called micro-dosingmicro dosingmicrodose
Microdosing means deliberately starting with a dose well below the usual standard or manufacturer recommendation. Behind it sits the principle "start low, go slow": you first test your own reaction and tolerability and work up only in small steps, instead of beginning at the full dose. This lowers the mostly dose-dependent side effects.
As long as you stay below or between the official dose steps and do not exceed the total amount intended for the duration of use, you are deliberately staying on the cautious side of the official range. Important: microdosing is not an approved dosing scheme, an added benefit at mini-doses is not scientifically proven, and it does not replace medical advice.
More in the guide Microdosing with peptides. To convert a chosen amount into the tick marks (units) on the syringe and the necessary bacteriostatic water, use the injection calculator (no dosing recommendation).
Related terms
Sources
- Frontiers in Endocrinology (PMC): slower GLP-1 titration lowers nausea and dropouts at equal efficacy
- STAT News: Microdosing GLP-1 drugs - US prevalence, lack of clinical evidence
- Science-Based Medicine: "Start low, go slow" - origin and pharmacological rationale
- GoodRx: Microdosing GLP-1s - benefits, risks, evidence