Peptipedia › Glossary › Titration
Use & dosing
Titration
Titration - Easing up to the target dose: start low and increase slowly so the body can adapt and side effects stay smaller.
Also called dose ramptitrating uptitration
Titration means adjusting the dose toward a target step by step, usually „start low, go slow": begin with a low dose and raise it at intervals.
Why it's done
Easing up gives the body time to adapt and keeps early side effects smaller than starting high at once. A well-known example is the so-called GLP-1 drugs (a modern class of active ingredients found in diabetes medicines and newer „weight-loss injections" such as semaglutide/Wegovy): these can cause nausea early on, and ramping the dose slowly helps keep that milder.
Wording mix-ups
Don't confuse it with the chemistry lab „titration" (measuring concentration). Here it means ramping the dose.